妊娠毒血症

2017-02-06 16:36 阅读: 编辑:sunyoung 来源:家有宝宝
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内容简介:妊娠毒血症是孕畜所特有的疾病,多发生于妊娠中、后期。本病发生于怀骡母畜及双胎母羊,以怀骡母驴最为多见,偶尔在驴怀驴、马怀马时见到,在我国北方各地均有发生。
       妊娠毒血症(Pre-eclampsia),又称子癎前症、产前子痫症,是指孕畜在怀孕期间,发生血压上升(妊娠型高血压),合并蛋白尿、水肿等现象。妊娠毒血症是一系列的症候,而不是来自于单一的致病因子,有许多不同的原因可能引起这个状况。它有可能是来自某种物质,透过胎盘,进入孕妇的身体,导致孕妇血管的内皮组织功能异常所导致。它所造成的高血压,可能会造成内皮细胞、肾脏与肝脏的损害;因此造成血管收缩因子释放至血管中,形成二次伤害。如果孕畜因此产生全身痉挛的现象,则称为子癎。(推荐阅读:妊娠中毒

妊娠毒血症 孕期疾病


       病因


       病因尚不完全清楚,目前认为主要与营养失调和运动不足有关。品种、年龄、肥胖、胎次、怀胎过多、胎儿过大、妊娠期营养不良及环境变化等因素均可影响本病的发生。

       本病的发生首先是体内肝糖元被消耗,接着动员体脂去调节血中葡萄糖平衡,结果造成大量脂肪积聚于肝脏和游离于血液中,造成脂肪肝和高血脂,肝功能衰竭,有机酮和有机酸大量积聚,导致酮血症和酸中毒;大量酮体经肾脏排出时,又使肾脏发生脂肪变性,有毒物质更加无法排出,造成尿毒症;同时因机体不能完成调节葡萄糖平衡而出现低血糖。因此,妊娠毒血症是酮血症、酸中毒、低血糖和肝功能衰竭的综合症。

       病理变化


       以心、肝、肾、脾及胃肠道病变明显。肝脏明显肿大,色黄或土黄,质脆弱易碎,有不同程度的胆汁淤滞,切面油腻,肝小叶充血,个别有坏死病变;肾脏稍肿大,包膜粘连,多有黄色条斑或出血区,肾上腺肿胀,皮质及髓质明显充血、出血,并有严重的脂变;心脏柔软,心肌变性,色淡,有灰黄色斑块,心内外膜有大小不等的出血斑点,心室扩张;脾脏严重的充血和出血;甲状腺萎缩;胃肠浆膜及黏膜下多有出血性及坏死性炎症,小肠病变比大肠严重;胎水量多,呈污红色;腹水增多。

       症状


       轻者症状不明显,重者可见精神沉郁,呼吸困难,尿量严重减少,呼出气体有酮味。死前可发生流产、共济失调,惊厥及昏迷等症状。血液学检查非蛋白氮升高,钙减少,磷增加,丙酮试验阳性。

       预防


       预防上,在妊娠后期防止营养不足,应供给富含蛋白质和碳水化合物并易消化的饲料,不喂劣质饲料。同时应避免突然更换饲料及其它应激因素。对肥胖、怀胎过多过大,以及易发生该病的品种,可在分娩前后适当补给葡萄糖,可防止妊娠毒血症的发生与发展。

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